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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPD4
All Species:
22.12
Human Site:
S712
Identified Species:
48.67
UniProt:
Q9NXE4
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NXE4
NP_060221.2
827
93352
S712
V
R
T
L
F
R
L
S
S
A
I
N
H
R
F
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543560
827
93189
S712
V
R
M
L
F
R
L
S
S
A
I
N
C
R
F
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZPR5
823
93257
S708
V
R
A
L
F
R
L
S
S
A
I
N
R
R
F
Rat
Rattus norvegicus
NP_001161278
823
93261
S708
V
R
A
L
F
R
L
S
S
A
I
N
R
R
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509989
509
58534
S395
V
R
L
L
F
Q
V
S
S
A
I
N
R
R
F
Chicken
Gallus gallus
XP_415236
827
94779
S713
V
R
L
L
Y
R
L
S
S
A
L
N
E
R
L
Frog
Xenopus laevis
Q5XHG1
824
93777
Y709
A
M
L
V
R
Y
L
Y
R
L
S
S
V
I
N
Zebra Danio
Brachydanio rerio
Q6PFJ7
791
89972
L674
N
A
F
L
V
R
L
L
F
Q
I
S
S
F
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650124
767
86929
R651
P
I
Q
T
N
E
V
R
A
L
V
R
M
L
H
Honey Bee
Apis mellifera
XP_623882
744
86631
M630
Y
R
H
K
I
T
R
M
Y
H
E
S
G
F
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784153
874
98584
S742
V
R
V
L
H
A
L
S
C
Q
F
N
D
A
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
92
N.A.
89.8
90.3
N.A.
46.1
74.9
66.2
60.5
N.A.
24.2
29.5
N.A.
31
Protein Similarity:
100
N.A.
N.A.
94.5
N.A.
93.8
93.9
N.A.
51.8
83.9
77.6
71.9
N.A.
42.2
47.4
N.A.
49.2
P-Site Identity:
100
N.A.
N.A.
86.6
N.A.
86.6
80
N.A.
73.3
66.6
6.6
26.6
N.A.
0
13.3
N.A.
46.6
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
86.6
80
N.A.
86.6
80
20
33.3
N.A.
20
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
19
0
0
10
0
0
10
55
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
0
10
0
10
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
10
0
0
0
0
10
0
10
0
0
% E
% Phe:
0
0
10
0
46
0
0
0
10
0
10
0
0
19
55
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% G
% His:
0
0
10
0
10
0
0
0
0
10
0
0
10
0
10
% H
% Ile:
0
10
0
0
10
0
0
0
0
0
55
0
0
10
10
% I
% Lys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
28
73
0
0
73
10
0
19
10
0
0
10
10
% L
% Met:
0
10
10
0
0
0
0
10
0
0
0
0
10
0
0
% M
% Asn:
10
0
0
0
10
0
0
0
0
0
0
64
0
0
10
% N
% Pro:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
10
0
0
10
0
0
0
19
0
0
0
0
0
% Q
% Arg:
0
73
0
0
10
55
10
10
10
0
0
10
28
55
0
% R
% Ser:
0
0
0
0
0
0
0
64
55
0
10
28
10
0
0
% S
% Thr:
0
0
10
10
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
64
0
10
10
10
0
19
0
0
0
10
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
10
10
0
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _